Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739089 | 0.88 | KMT2A (0.73) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL13039486 | 0.85 | POLB (0.67) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL13039610 | 0.85 | POLB (0.76) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL3746207 | 0.84 | SMN1; SMN2 (0.64) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL3739166 | 0.82 | SMN1; SMN2 (0.53) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL13077413 | 0.81 | POLB (0.58) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL163365 | 0.81 | POLB (0.61) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL163937 | 0.81 | POLB (0.61) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL113832 | 0.81 | SMN1; SMN2 (0.53) | KMT2ARAB9APOLBGAAEIF4H | |
| SCHEMBL3732854 | 0.81 | SMN1; SMN2 (0.53) | KMT2ARAB9APOLBGAAEIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126811-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-04 | — | — | WO | disclosed |