Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TYR | P14679 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820225 | 0.78 | PDE10A (0.58) | ALOX15ALDH1A1CYP2C9HSD17B10ALOX5 | |
| Methylhydroquinone SCHEMBL36349 | 0.72 | — | — | |
| Methylhydroquinone SCHEMBL10426478 | 0.72 | TP53 (0.62) | ALOX15ALDH1A1TYRLMNACYP2C9 | |
| Methylhydroquinone SCHEMBL29364957 | 0.72 | — | — | |
| Methylhydroquinone SCHEMBL11664779 | 0.70 | TP53 (0.59) | ALOX15ALDH1A1TYRLMNACYP2C9 | |
| Methylhydroquinone SCHEMBL30471824 | 0.70 | TP53 (0.59) | ALOX15ALDH1A1TYRLMNACYP2C9 | |
| Methylhydroquinone SCHEMBL612972 | 0.70 | TP53 (0.59) | ALOX15ALDH1A1CYP2C9HSD17B10TDP1 | |
| Methylhydroquinone SCHEMBL537277 | 0.70 | TP53 (0.59) | ALOX15ALDH1A1CYP2C9HSD17B10TDP1 | |
| Methylhydroquinone SCHEMBL27680187 | 0.70 | TP53 (0.59) | ALOX15ALDH1A1TYRLMNACYP2C9 | |
| SCHEMBL14403784 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129049-A1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-11-11 | — | — | WO | disclosed |