Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774728 | 0.82 | POLB (0.36) | POLBTDP1CTDSP1 | |
| SCHEMBL4422295 | 0.80 | POLB (0.44) | POLBTDP1CTDSP1LMNAALDH1A1 | |
| SCHEMBL284782 | 0.80 | GABRR1 (0.36) | POLBTDP1CTDSP1LMNAALDH1A1 | |
| SCHEMBL4422298 | 0.80 | POLB (0.44) | POLBTDP1CTDSP1LMNAALDH1A1 | |
| SCHEMBL27438497 | 0.80 | POLB (0.44) | POLBTDP1CTDSP1LMNAALDH1A1 | |
| SCHEMBL27825601 | 0.78 | GABRR1 (0.34) | POLBTDP1CTDSP1LMNAALDH1A1 | |
| SCHEMBL19604954 | 0.78 | GABRR1 (0.34) | POLBTDP1CTDSP1LMNAALDH1A1 | |
| SCHEMBL2773116 | 0.78 | POLB (0.34) | POLBTDP1CTDSP1 | |
| SCHEMBL2773113 | 0.78 | POLB (0.34) | POLBTDP1CTDSP1 | |
| Hydrochloric Acid SCHEMBL9659824 | 0.77 | GABRR1 (0.43) | POLBTDP1CTDSP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9764038-B2 | Enzymatic conjugation of antibodies | INNATE PHARMA (FR) | 2017-09-19 | — | — | US | disclosed |
| US-9660277-B2 | Methods for inhibiting corrosion in brazed metal surfaces and coolants and additives for use therein | PRESTONE PRODUCTS CORPORATION (US) | 2017-05-23 | — | — | US | disclosed |
| US-20100276629-A1 | METHOD FOR STABILIZING AN ENGINE COOLANT CONCENTRATE AND PREVENTING HARD WATER SALT FORMATION UPON DILUTION | FRAM GROUP IP LLC | 2010-11-04 | — | — | US | disclosed |
| US-20100196773-A1 | METHODS FOR INHIBITING CORROSION IN BRAZED METAL SURFACES AND COOLANTS AND ADDITIVES FOR USE THEREIN | HONEYWELL INTERNATIONAL INC. (US) | 2010-08-05 | — | — | US | disclosed |
| US-7754097-B2 | Method for stabilizing an engine coolant concentrate and preventing hard water salt formation upon dilution | HONEYWELL INTERNATIONAL INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070075120-A1 | Methods for inhibiting corrosion in brazed metal surfaces and coolants and additives for use therein | GOLDMAN SACHS MIDDLE MARKET LENDING CORP. II | 2007-04-05 | — | — | US | disclosed |
| US-20070034826-A1 | making stabilized concentrate by adding to coolant concentrate at least one stabilizer selected from polyacrylate polymers, concentrate comprising 90 or more wt % freezing point depressant, then diluting stabilized coolant concentrate with hard water to provide final coolant composition | PRESTONE PRODUCTS CORPORATION (US) | 2007-02-15 | — | — | US | disclosed |