SCHEMBL13079877

SCHEMBL13079877

C[Si](C)(C)OC12CC3CCC(CC(C3)C1)C2

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.39
GRIN2D O15399 2/20 0.31
GRIN3B O60391 2/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2A Q12879 2/20 0.31
GRIN2B Q13224 2/20 0.31
GRIN2C Q14957 2/20 0.31
GRIN3A Q8TCU5 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12900034 0.93 NPSR1 (0.43) NPSR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL13079875 0.77 NPSR1 (0.32) NPSR1
SCHEMBL8584936 0.75 NPSR1 (0.44) NPSR1
SCHEMBL4285723 0.71 NPSR1 (0.38) NPSR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL12900032 0.71 NPSR1 (0.34) NPSR1
SCHEMBL14501194 0.70 NPSR1 (0.36) NPSR1
SCHEMBL13079876 0.66 CA9 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL18576245 0.65 NPSR1 (0.36) NPSR1
SCHEMBL18417885 0.65 HTT (0.36) SMN1; SMN2
SCHEMBL727714 0.64 NPSR1 (0.48) NPSR1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283103-B2 Composition for forming resist underlayer film for lithography and production method of semiconductor device NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-10-09 US disclosed