Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738583 | 0.85 | KMT2A (0.49) | KMT2ATRPM8SSTR4SSTR5NR2E1 | |
| SCHEMBL13081976 | 0.82 | SSTR4 (0.50) | KMT2ATRPM8SSTR4SSTR5SSTR2 | |
| SCHEMBL377599 | 0.70 | NR2E1 (0.54) | KMT2ANR2E1MEN1KDM4EALDH1A1 | |
| SCHEMBL21754369 | 0.67 | NR2E1 (0.75) | NR2E1KDM4EALDH1A1MAPT | |
| SCHEMBL30866199 | 0.66 | NR2E1 (0.52) | KMT2ATRPM8NR2E1MEN1KDM4E | |
| SCHEMBL19161254 | 0.66 | KMT2A (0.73) | KMT2ATRPM8MEN1KDM4EALDH1A1 | |
| SCHEMBL19138937 | 0.66 | KMT2A (0.73) | KMT2ATRPM8MEN1KDM4EALDH1A1 | |
| SCHEMBL12564952 | 0.65 | KDM4E (0.50) | TRPM8NR2E1KDM4ECYP19A1 | |
| SCHEMBL19138900 | 0.64 | KMT2A (0.77) | KMT2ATRPM8MEN1KDM4EALDH1A1 | |
| SCHEMBL19138982 | 0.64 | KMT2A (0.70) | KMT2ATRPM8MEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133806-A2 | MARKED PEPTIDES AND USE THEREOF FOR ASSAYING CIRCULATING IRAP | UNIVERSITE JOSEPH FOURIER (FR) | 2010-11-25 | — | — | WO | disclosed |