Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.78 |
| ▸ | POLA1 | P09884 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.70 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.60 |
| ▸ | VDR | P11473 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | OSBP | P22059 | 1/20 | 0.56 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | FGF1 | P05230 | 1/20 | 0.55 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26693323 | 1.00 | CDC25A (0.78) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL26912861 | 1.00 | CDC25A (0.78) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL19184920 | 1.00 | CDC25A (0.78) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL11994855 | 1.00 | CDC25A (0.78) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL4735227 | 1.00 | CDC25A (0.78) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL23813359 | 1.00 | CDC25A (0.78) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL10017499 | 0.93 | CDC25A (0.68) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL12086538 | 0.93 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL15113084 | 0.93 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL4739096 | 0.93 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283456-B2 | Triterpene saponins, methods of synthesis, and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2012-10-09 | — | — | US | disclosed |