Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 12/20 | 0.49 |
| ▸ | MTTP | P55157 | 7/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13085075 | 0.94 | NPY2R (0.50) | NPY2RMTTPKCNQ2ALDH1A1MAPT | |
| SCHEMBL13084968 | 0.93 | NPY2R (0.50) | NPY2RMTTPKCNQ2EP300 | |
| SCHEMBL2582743 | 0.93 | NPY2R (0.57) | NPY2RMTTPKCNQ2EP300ALDH1A1 | |
| SCHEMBL12174513 | 0.86 | NPY2R (0.58) | NPY2RMTTPALDH1A1 | |
| SCHEMBL12174495 | 0.86 | NPY2R (0.66) | NPY2RMTTPKCNQ2ALDH1A1MAPT | |
| SCHEMBL12174506 | 0.85 | NPY2R (0.58) | NPY2RMTTPKCNQ2EP300ALDH1A1 | |
| SCHEMBL13085262 | 0.84 | NPY2R (0.46) | NPY2RMTTPKCNQ2HTR1ES1PR3 | |
| SCHEMBL12174395 | 0.84 | NPY2R (0.65) | NPY2RMTTPKCNQ2GAA | |
| SCHEMBL13085173 | 0.84 | NPY2R (0.46) | NPY2RMTTPKCNQ2KDM4EALDH1A1 | |
| SCHEMBL12174193 | 0.83 | NPY2R (0.56) | NPY2RMTTPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317431-B1 | POLYARYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-20 | — | — | EP | disclosed |