Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 9/20 | 0.49 |
| ▸ | MTTP | P55157 | 5/20 | 0.49 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12174411 | 0.92 | NPY2R (0.56) | NPY2RMTTPEP300MAPTMAPK1 | |
| SCHEMBL13085083 | 0.90 | MTTP (0.49) | NPY2RMTTP | |
| SCHEMBL13085101 | 0.87 | NPY2R (0.46) | NPY2RMTTPMAPTMAPK1TSHR | |
| SCHEMBL12174527 | 0.85 | NPY2R (0.62) | NPY2RMTTPMAPTMAPK1TSHR | |
| SCHEMBL12174537 | 0.85 | NPY2R (0.67) | NPY2RMTTPEP300ALDH1A1 | |
| SCHEMBL12174526 | 0.84 | NPY2R (0.54) | NPY2RMTTPEP300MAPTMAPK1 | |
| SCHEMBL12174461 | 0.84 | NPY2R (0.55) | NPY2RMTTPMAPTMAPK1TSHR | |
| SCHEMBL13085189 | 0.84 | NPY2R (0.55) | NPY2RMTTPMAPTMAPK1TSHR | |
| SCHEMBL12174506 | 0.83 | NPY2R (0.58) | NPY2RMTTPEP300MAPTMAPK1 | |
| SCHEMBL12174544 | 0.83 | NPY2R (0.60) | NPY2RMTTPMAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317431-B1 | POLYARYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-20 | — | — | EP | disclosed |