Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058857 | 1.00 | HDAC3 (0.62) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL13087529 | 1.00 | HDAC3 (0.62) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL13087285 | 0.99 | HDAC3 (0.60) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL13087507 | 0.94 | HDAC3 (0.58) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL6763786 | 0.89 | HDAC3 (0.74) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL9191952 | 0.88 | HDAC3 (0.71) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL3233893 | 0.86 | HDAC3 (0.62) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL3233201 | 0.86 | HDAC3 (0.62) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL3238191 | 0.86 | HDAC3 (0.62) | HDAC3NCOR2NPC1RAB9AHDAC1 | |
| SCHEMBL1377409 | 0.85 | HDAC3 (0.68) | HDAC3NCOR2NPC1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261710-A1 | HDAC Inhibitors | ARQULE, INC. (US) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261710-A1 | HDAC Inhibitors | HDAC5, HDAC1, HDAC4 | HDAC3 7/4885NCOR2 120/4885NPC1 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.