Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13089735 | 0.86 | ELANE (0.42) | ELANECYP2C9CYP3A4ADRB1HTR1A | |
| SCHEMBL4547774 | 0.79 | ELANE (0.60) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8346759 | 0.79 | ELANE (0.54) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8239844 | 0.74 | ELANE (0.62) | ELANECYP2C9CYP3A4 | |
| SCHEMBL16298340 | 0.74 | ELANE (0.62) | ELANECYP2C9CYP3A4 | |
| SCHEMBL4547773 | 0.74 | ELANE (0.62) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8344934 | 0.73 | ELANE (0.48) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2678682 | 0.73 | ELANE (0.61) | ELANECYP2C9CYP3A4 | |
| SCHEMBL13089737 | 0.73 | ELANE (0.44) | ELANECYP2C9CYP3A4ADRB1HTR1A | |
| SCHEMBL2824680 | 0.71 | ELANE (0.63) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539710-B1 | HETEROCYCLIC DERIVATIVES | BAYER SCHERING PHARMA AG (DE) | 2010-10-27 | — | — | EP | disclosed |