Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13091030 | 0.97 | APP (0.55) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL16183126 | 0.86 | APP (0.57) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL13745868 | 0.82 | APP (0.61) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL16091909 | 0.82 | APP (0.54) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL16091914 | 0.81 | APP (0.56) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL16183127 | 0.81 | APP (0.55) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL16091910 | 0.79 | APP (0.55) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL1105641 | 0.79 | APP (0.55) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL16091916 | 0.78 | APP (0.56) | APPBCHEACHEKDM4EPOLB | |
| SCHEMBL10118417 | 0.77 | APP (0.53) | APPBCHEACHEKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267078-A1 | Selective Detection of Proteins that Contain Two or More Alpha-Helical Transmembrane Domains | Life Technologies Corporation (US) | 2010-10-21 | — | — | US | disclosed |