Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.79 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.42 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096296 | 0.95 | CYP2D6 (0.79) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL13097533 | 0.88 | CYP2D6 (1.00) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL13097659 | 0.88 | CYP2D6 (0.65) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL3099144 | 0.87 | CYP2D6 (0.91) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL13097710 | 0.87 | CYP2D6 (0.71) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL13097528 | 0.86 | CYP2D6 (1.00) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL13097702 | 0.86 | CYP2D6 (0.73) | CYP2D6CTSVCTSL | |
| SCHEMBL13097535 | 0.85 | CYP2D6 (1.00) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL13097981 | 0.84 | CYP2D6 (0.66) | CYP2D6MCL1CTSVCTSL | |
| SCHEMBL13097648 | 0.83 | CYP2D6 (0.62) | CYP2D6MCL1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | CYP2D6 230/4885MCL1 3783/4885CTSV 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.