⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936620 | 0.97 | — | — | |
| SCHEMBL10196459 | 0.97 | — | — | |
| SCHEMBL8271926 | 0.97 | — | — | |
| SCHEMBL7624514 | 0.85 | CRBN (0.48) | — | |
| SCHEMBL21291413 | 0.80 | CRBN (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL5422446 | 0.80 | CRBN (0.39) | — | |
| SCHEMBL15007205 | 0.78 | CRBN (0.41) | — | |
| SCHEMBL31681246 | 0.75 | CRBN (0.38) | — | |
| SCHEMBL24364277 | 0.74 | — | — | |
| SCHEMBL24553181 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329853-B2 | Process for the preparation of poly-α-glutamic acid and derivatives thereof | CELL THERAPEUTICS, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2027145-B1 | A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF | CELL THERAPEUTICS INC SEDE SECONDARIA (IT) | 2012-03-07 | — | — | EP | disclosed |
| EP-2364992-A1 | A process for the preparation of poly-alfa-glutamic acid and derivatives thereof | Cell Therapeutics, Inc. - Sede Secondaria (IT) | 2011-09-14 | — | — | EP | disclosed |
| EP-2364991-A1 | A process for the preparation of poly-alfa-glutamic acid and derivatives thereof | Cell Therapeutics, Inc. - Sede Secondaria (IT) | 2011-09-14 | — | — | EP | disclosed |
| US-20110196123-A1 | PROCESS FOR THE PREPARATION OF POLY-alpha-GLUTAMIC ACID AND DERIVATIVES THEREOF | CELL THERAPEUTICS, INC. (US) | 2011-08-11 | — | — | US | disclosed |
| EP-2027145-A1 | A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF | Cell Therapeutics, Inc. - Sede Secondaria (IT) | 2009-02-25 | — | — | EP | disclosed |
| US-20080051603-A1 | Process for the preparation of poly-alpha-glutamic acid and derivatives thereof | CELL THERAPEUTICS, INC. (US) | 2008-02-28 | — | — | US | disclosed |
| WO-2007144140-A1 | A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF | CELL THERAPEUTICS INC. - SEDE SECONDARIA (IT) | 2007-12-21 | — | — | WO | disclosed |
| EP-1867657-A1 | Process for the preparation of poly-a-glutamic acid and derivatives thereof | Cell Therapeutics Europe S.R.L. (IT) | 2007-12-19 | — | — | EP | disclosed |