⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460050 | 0.83 | — | — | |
| SCHEMBL22978478 | 0.82 | KDM4A (0.52) | — | |
| SCHEMBL23300622 | 0.82 | CYP2C19 (0.44) | — | |
| SCHEMBL8531697 | 0.76 | IDO1 (0.44) | — | |
| SCHEMBL20601188 | 0.76 | CYP2C19 (0.39) | — | |
| SCHEMBL3615987 | 0.76 | — | — | |
| SCHEMBL20601187 | 0.75 | CYP2C19 (0.38) | — | |
| SCHEMBL6534542 | 0.75 | CYP2C19 (0.38) | — | |
| SCHEMBL28468147 | 0.75 | CYP2C19 (0.38) | — | |
| SCHEMBL8548799 | 0.75 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530646-B2 | Oxazolidinone derivative having 7-membered hetero ring | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20100256355-A1 | OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING | Research Foundation ITSUU Laboratory and Shionogi & Co., Ltd. | 2010-10-07 | — | — | US | disclosed |