Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.45 |
| ▸ | ACACA | Q13085 | 11/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13103228 | 0.92 | ACACB (0.52) | ACACBACACA | |
| SCHEMBL13103222 | 0.86 | ACACB (0.58) | ACACBACACA | |
| SCHEMBL13103243 | 0.86 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL13103237 | 0.81 | ACACB (0.34) | ACACBACACA | |
| SCHEMBL37090 | 0.80 | ACACB (0.38) | ACACBACACA | |
| SCHEMBL13039858 | 0.80 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL15472959 | 0.80 | ACACB (0.40) | ACACBACACA | |
| SCHEMBL12285257 | 0.78 | ACACB (0.38) | ACACBACACA | |
| SCHEMBL12362105 | 0.78 | ACACB (0.38) | ACACBACACANPC1RAB9A | |
| SCHEMBL12362070 | 0.78 | ACACB (0.39) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846946-B2 | Germinal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8846946-B2 | Germinal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2014-09-30 | — | — | US | disclosed |
| EP-2373619-B1 | GEMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMIC ACID DERIVATES | BAYER CROPSCIENCE AG (DE) | 2014-09-10 | — | — | EP | disclosed |
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-8389443-B2 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| US-8389443-B2 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| WO-2010063378-A1 | GEMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMIC ACID DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | AGXT, GMNN, GLRX3 | ACACB 496/4885ACACA 222/4885NR2F2 4040/4885 |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | GMNN, AGXT, GEMIN5 | ACACB 643/4885ACACA 281/4885NR2F2 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.