Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.48 |
| ▸ | ACACA | Q13085 | 8/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910066 | 1.00 | ACACB (0.48) | ACACBACACAABCB1 | |
| SCHEMBL16131089 | 0.92 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL13103282 | 0.88 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL15910065 | 0.88 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL15300245 | 0.84 | ACACB (0.35) | ACACBACACA | |
| SCHEMBL13103234 | 0.84 | ACACB (0.41) | ACACBACACAABCB1 | |
| SCHEMBL15472957 | 0.82 | ACACB (0.33) | ACACBACACAABCB1 | |
| SCHEMBL13103226 | 0.81 | ACACB (0.38) | ACACBACACA | |
| SCHEMBL13117629 | 0.81 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL12362050 | 0.79 | NPC1 (0.31) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373619-B1 | GEMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMIC ACID DERIVATES | BAYER CROPSCIENCE AG (DE) | 2014-09-10 | — | — | EP | disclosed |
| US-8389443-B2 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| US-8389443-B2 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| WO-2010063378-A1 | GEMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMIC ACID DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | GMNN, AGXT, GEMIN5 | ACACB 643/4885ACACA 281/4885ABCB1 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.