Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | THRB | P10828 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104772 | 0.97 | KDM4E (0.53) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL13104748 | 0.92 | KDM4E (0.54) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL13104780 | 0.87 | MAPT (0.69) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL13104757 | 0.84 | MAPT (0.61) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL13104752 | 0.84 | MAPT (0.62) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL14444987 | 0.84 | MAPT (0.60) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL13104753 | 0.82 | KDM4E (0.40) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL12588678 | 0.80 | MAPT (0.56) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL4621970 | 0.79 | MAPT (0.79) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL13104779 | 0.79 | MAPT (0.64) | MAPTTHRBKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807075-B2 | Photochromic compositions and light transmissible articles | ADVANCED POLYMERIK PTY LTD (AU) | 2010-10-05 | — | — | US | disclosed |
| US-20080006798-A1 | Photochromic Compositions and Light Transmissible Articles | JAMES ROBINSON SPECIALITY INGREDIENTS LTD (GB) | 2008-01-10 | — | — | US | disclosed |
| US-7247262-B2 | Photochromic compositions and light transmissible articles | POLYMERS AUSTRALIA PTY LTD. (AU) | 2007-07-24 | — | — | US | disclosed |