⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573418 | 0.74 | — | — | |
| SCHEMBL10458278 | 0.73 | — | — | |
| SCHEMBL875662 | 0.71 | — | — | |
| SCHEMBL27668660 | 0.71 | — | — | |
| SCHEMBL1275713 | 0.71 | — | — | |
| SCHEMBL17628539 | 0.71 | CA12 (0.53) | — | |
| Hydrochloric Acid SCHEMBL10943425 | 0.69 | — | — | |
| SCHEMBL16235713 | 0.69 | CA12 (0.50) | — | |
| SCHEMBL20679745 | 0.69 | — | — | |
| SCHEMBL697915 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8052983-B2 | Administering a photosensitive, non-antibiotic tetracycline, preferably chosen from CMT-1 through CMT-10, without administering a bisphosphonate compound; side effect reduction | GALDERMA LABORATORIES, INC. (US) | 2011-11-08 | — | — | US | claimed |
| EP-1505961-A4 | METHODS OF TREATING ALLERGIC REACTIONS | COLLAGENEX PHARM INC (US) | 2009-09-02 | — | — | EP | claimed |
| US-20090137845-A1 | Novel 4-Dedimethylaminotetracycline derivatives | GALDERMA LABORATORIES INC. | 2009-05-28 | — | — | US | claimed |
| EP-1494681-A4 | METHODS OF SIMULTANEOUSLY TREATING OCULAR ROSACEA AND ACNE ROSACEA | COLLAGENEX PHARM INC (US) | 2008-08-06 | — | — | EP | claimed |
| US-20080171727-A1 | METHODS OF TREATING ACNE | GALDERMA LABORATORIES INC. | 2008-07-17 | — | — | US | claimed |
| EP-1716856-A2 | The treatment of acne | Collagenex Pharmaceuticals, Inc. (US) | 2006-11-02 | — | — | EP | claimed |
| EP-1137410-B1 | NOVEL 4-DEDIMETHYL AMINOTETRACYCLINE DERIVATIVES | COLLAGENEX PHARM INC (US) | 2006-08-16 | — | — | EP | claimed |
| US-20060094697-A1 | Methods of simultaneously treating ocular rosacea and acne rosacea | COLLAGENEX PHARMACEUTCALS, INC. | 2006-05-04 | — | — | US | claimed |
| US-7014858-B2 | Use methods of treating acne and telangiectasia | COLLAGENEX PHARMACEUTICALS, INC. (US) | 2006-03-21 | — | — | US | claimed |
| US-20050171068-A1 | Novel 4-dedimethylaminotetracycline derivatives | COLLAGENEX PHARMACEUTICALS, INC. | 2005-08-04 | — | — | US | claimed |
| WO-2002080932-A1 | METHODS OF TREATING ACNE | COLLAGENEX PHARMACEUTICALS, INC. (US) | 2002-10-17 | — | — | WO | claimed |
| EP-1137410-A4 | NOVEL 4-DEDIMETHY LAMINOTETRA CYCLINE DERIVATIVES | COLLAGENEX PHARM INC (US) | 2002-06-26 | — | — | EP | claimed |
| WO-2001087823-A1 | NOVEL ARYL, ALKENYL, AND ALKYNL 4-DEDIMETHYLAMINOTETRACYCLINE DERIVATIVES | COLLAGENEX PHARMACEUTICALS, INC. (US) | 2001-11-22 | — | — | WO | claimed |
| EP-1137410-A1 | NOVEL 4-DEDIMETHY LAMINOTETRA CYCLINE DERIVATIVES | Collagenex Pharmaceuticals, Inc. (US) | 2001-10-04 | — | — | EP | claimed |
| EP-1124558-A2 | A NOVEL INHIBITOR OF CATARACT FORMATION | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000028983-A1 | NOVEL 4-DEDIMETHY LAMINOTETRA CYCLINE DERIVATIVES | COLLAGENEX PHARMACEUTICALS, INC. (US) | 2000-05-25 | — | — | WO | claimed |
| WO-2000018353-A2 | A NOVEL INHIBITOR OF CATARACT FORMATION | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-04-06 | — | — | WO | claimed |
| EP-0117875-B1 | PROCESS FOR PREPARING AZETIDINONE DERIVATIVES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1987-07-22 | — | — | EP | claimed |
| US-4622178-A | CEPHALOSPORIN INTERMEDIATES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-11-11 | — | — | US | claimed |
| US-4410522-A | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | claimed |