Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110259 | 1.00 | NPY1R (0.50) | NPY1RNPY2RNPY4RNPY5RDDB1 | |
| SCHEMBL12169265 | 0.92 | NPY1R (0.56) | NPY1RNPY2RNPY4RNPY5RDDB1 | |
| SCHEMBL13439683 | 0.89 | NPY1R (0.47) | NPY1RNPY2RNPY4RNPY5RDDB1 | |
| SCHEMBL13403331 | 0.87 | NPY1R (0.51) | NPY1RNPY2RNPY4RNPY5RDDB1 | |
| SCHEMBL9640923 | 0.86 | HRH1 (0.43) | MAPTACACBHRH3SMN1; SMN2 | |
| SCHEMBL16437278 | 0.85 | NPY1R (0.57) | NPY1RNPY2RNPY4RNPY5RDDB1 | |
| SCHEMBL11937222 | 0.85 | NPY1R (0.62) | NPY1RNPY2RNPY4RNPY5RDDB1 | |
| SCHEMBL13110214 | 0.84 | NPY1R (0.49) | NPY1RNPY2RNPY4RNPY5RDDB1 | |
| SCHEMBL16579467 | 0.84 | TEAD1 (0.52) | TEAD1 | |
| SCHEMBL26796088 | 0.83 | NPY1R (0.47) | NPY1RNPY2RNPY4RNPY5RDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |