Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 11/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110407 | 0.94 | FFAR1 (0.61) | FFAR1PPARDPPARAPPARGFFAR4 | |
| SCHEMBL13110431 | 0.94 | FFAR1 (0.61) | FFAR1PPARDPPARAPPARGFFAR4 | |
| SCHEMBL3964811 | 0.92 | FFAR1 (0.63) | FFAR1PPARDPPARAPPARG | |
| SCHEMBL3451166 | 0.88 | PPARD (0.69) | FFAR1PPARDPPARAFFAR4 | |
| SCHEMBL13110422 | 0.84 | FFAR1 (0.81) | FFAR1 | |
| SCHEMBL3450438 | 0.82 | FFAR1 (0.69) | FFAR1PPARDPPARAPPARGFFAR4 | |
| SCHEMBL12214716 | 0.82 | PPARD (0.50) | FFAR1PPARDPPARAPPARG | |
| SCHEMBL3449531 | 0.81 | FFAR1 (0.70) | FFAR1PPARDPPARAPPARGFFAR4 | |
| SCHEMBL3965769 | 0.79 | PPARD (0.74) | FFAR1PPARDPPARAPPARG | |
| SCHEMBL3962234 | 0.79 | PPARD (0.74) | FFAR1PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |