SCHEMBL13110477

SCHEMBL13110477

CCCC1CCC(c2ccc(C)c(Cl)c2F)CC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 17/20 0.40
CYP2C9 P11712 1/20 0.38
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13235249 0.96 OPRL1 (0.38) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL12716105 0.86 OPRL1 (0.43) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL14235341 0.86 OPRL1 (0.43) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL14824862 0.86 NOTUM (0.35) OPRL1
SCHEMBL13110473 0.85 OPRL1 (0.40) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL13235237 0.84 OPRL1 (0.34) OPRL1
SCHEMBL4406898 0.82 OPRL1 (0.40) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL12140866 0.82 OPRL1 (0.40) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL3437350 0.82 OPRL1 (0.40) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL17614851 0.82 OPRL1 (0.40) OPRL1CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820072-B2 Liquid crystalline medium and method for manufacturing liquid crystal display panel A U OPTRONICS CORP. (TW) 2010-10-26 US disclosed
US-20080236727-A1 Liquid crystalline medium and method for manufacturing liquid crystal display panel AU OPTRONICS CORP. (TW) 2008-10-02 US disclosed