Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110834 | 0.90 | HDAC1 (0.51) | HDAC1HDAC2HDAC3HDAC6HDAC7 | |
| SCHEMBL12632924 | 0.88 | HDAC1 (0.49) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL13110784 | 0.85 | HDAC1 (0.56) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL13110770 | 0.84 | HDAC1 (0.62) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL13110983 | 0.84 | HDAC1 (0.62) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL13110782 | 0.80 | HDAC1 (0.51) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL8348119 | 0.80 | HDAC1 (0.70) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL13110975 | 0.80 | HDAC1 (0.57) | HDAC1HDAC2HDAC3NCOR2HDAC6 | |
| SCHEMBL13110776 | 0.80 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC6HDAC7 | |
| SCHEMBL13110972 | 0.79 | HDAC1 (0.54) | HDAC1HDAC2HDAC3NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | SYNDAX PHARMACEUTICALS, INC. (US) | 2010-10-21 | — | — | US | disclosed |
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | SYNDAX PHARMACEUTICALS, INC. (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | HDAC1, HDAC3, HDAC6 | HDAC1 1/4885HDAC2 6/4885HDAC3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.