Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | PRKCA | P17252 | 5/20 | 0.79 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.79 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.79 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110574 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL13110571 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL13110576 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL13110570 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL29411373 | 0.93 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL10964504 | 0.92 | MAPT (0.77) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL9503254 | 0.92 | MAPT (0.77) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL23794943 | 0.90 | MAPT (0.75) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL9070261 | 0.90 | MAPT (0.75) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL7416016 | 0.90 | MAPT (0.75) | MAPTMAPK1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820803-B2 | Immobilized phosphatidic acid probe | Holmes, Andrew Bruce (GB) | 2010-10-26 | — | — | US | disclosed |