Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MTTP | P55157 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110806 | 0.92 | HDAC1 (0.45) | HDAC1HDAC2HDAC3MAPK14MTTP | |
| SCHEMBL13110748 | 0.91 | HDAC1 (0.54) | HDAC1HDAC2HDAC3PTGS1HDAC8 | |
| SCHEMBL13110854 | 0.80 | UTS2R (0.45) | HDAC1HDAC2HDAC3MDM4TP53 | |
| SCHEMBL8084513 | 0.79 | HDAC1 (0.42) | HDAC1HDAC2HDAC3MAPK14MEN1 | |
| SCHEMBL13111067 | 0.79 | HDAC1 (0.47) | HDAC1HDAC2HDAC3MDM4TP53 | |
| SCHEMBL13111073 | 0.79 | TRPV1 (0.41) | HDAC1HDAC2HDAC3MTTPPTGS1 | |
| SCHEMBL13110844 | 0.78 | HDAC1 (0.47) | HDAC1HDAC2HDAC3MDM4TP53 | |
| SCHEMBL13110843 | 0.76 | HDAC1 (0.43) | HDAC1HDAC2HDAC3MDM4TP53 | |
| SCHEMBL8088353 | 0.76 | HDAC1 (0.43) | HDAC1HDAC2HDAC3MDM4TP53 | |
| SCHEMBL8078209 | 0.75 | HDAC1 (0.43) | HDAC1HDAC2HDAC3NAMPTMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | SYNDAX PHARMACEUTICALS, INC. (US) | 2010-10-21 | — | — | US | disclosed |
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | SYNDAX PHARMACEUTICALS, INC. (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267779-A1 | Novel Compounds and Methods of Using Them | HDAC1, HDAC3, HDAC6 | HDAC1 1/4885HDAC2 6/4885HDAC3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.