Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.79 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.70 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.70 |
| ▸ | AKT1 | P31749 | 3/20 | 0.67 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.65 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | AKT2 | P31751 | 2/20 | 0.51 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13111076 | 1.00 | SMPD1 (0.79) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL13111174 | 0.98 | SMPD1 (0.79) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL13111089 | 0.98 | SMPD1 (0.79) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL13111080 | 0.98 | SMPD1 (0.79) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL13111065 | 0.98 | SMPD1 (0.82) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL13111091 | 0.98 | SMPD1 (0.79) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL13111424 | 0.92 | SMPD1 (0.70) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL13111418 | 0.91 | SMPD1 (0.72) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL23037461 | 0.91 | SMPD1 (0.96) | SMPD1NR5A2NR5A1AKT1PLCG2 | |
| SCHEMBL8821828 | 0.91 | SMPD1 (0.96) | SMPD1NR5A2NR5A1AKT1PLCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820803-B2 | Immobilized phosphatidic acid probe | Holmes, Andrew Bruce (GB) | 2010-10-26 | — | — | US | disclosed |