Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114674 | 0.92 | CNR1 (0.50) | CNR1CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL3550428 | 0.80 | CNR1 (0.59) | CNR1CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL4805900 | 0.78 | CNR1 (0.62) | CNR1CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL13114732 | 0.78 | CNR1 (0.45) | CNR1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13114750 | 0.76 | CNR1 (0.52) | CNR1CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL5796174 | 0.76 | CNR1 (0.54) | CNR1CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL13114741 | 0.76 | CNR1 (0.59) | CNR1CYP2C9CYP2C19CYP3A4LMNA | |
| SCHEMBL14540420 | 0.75 | CNR1 (0.60) | CNR1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL14181067 | 0.75 | CNR1 (0.70) | CNR1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4807441 | 0.75 | CNR1 (0.70) | CNR1CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816357-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-19 | — | — | US | disclosed |