Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.67 |
| ▸ | CDK2 | P24941 | 7/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13121510 | 0.94 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121490 | 0.93 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954103 | 0.92 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954329 | 0.91 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121481 | 0.91 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121509 | 0.91 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121497 | 0.90 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL12953740 | 0.89 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121496 | 0.89 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121484 | 0.88 | GSK3B (0.69) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807683-B2 | N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2010-10-05 | — | — | US | disclosed |
| US-7807683-B2 | N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2010-10-05 | — | — | US | disclosed |