Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383344 | 1.00 | FYN (0.37) | FYNALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6394125 | 1.00 | FYN (0.37) | FYNALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1386664 | 1.00 | FYN (0.37) | FYNALDH1A1MAPTHPGDHSD17B10 | |
| Bromide SCHEMBL1605698 | 0.98 | FYN (0.36) | FYNALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1386152 | 0.79 | FYN (0.35) | FYNKDM4EGAANPSR1PDE4A | |
| SCHEMBL1385640 | 0.79 | SMN1; SMN2 (0.42) | FYNALDH1A1MAPTGAAPDE4B | |
| SCHEMBL1386530 | 0.79 | FYN (0.35) | FYNKDM4EGAANPSR1PDE4A | |
| SCHEMBL1386746 | 0.79 | SMN1; SMN2 (0.42) | FYNALDH1A1MAPTGAAPDE4B | |
| SCHEMBL5450660 | 0.79 | SMN1; SMN2 (0.42) | FYNALDH1A1MAPTGAAPDE4B | |
| SCHEMBL1384124 | 0.79 | SMN1; SMN2 (0.42) | FYNALDH1A1MAPTGAAPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807700-B2 | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 | AMGEN INC. (US) | 2010-10-05 | — | — | US | disclosed |