Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374966 | 0.92 | CXCR4 (0.45) | CXCR4 | |
| SCHEMBL3370742 | 0.88 | CXCR4 (0.50) | CXCR4 | |
| SCHEMBL5054280 | 0.77 | CXCR4 (0.54) | CXCR4 | |
| SCHEMBL3370911 | 0.77 | CXCR4 (0.78) | CXCR4 | |
| SCHEMBL3373767 | 0.77 | CXCR4 (0.44) | CXCR4 | |
| SCHEMBL5057529 | 0.77 | CXCR4 (0.58) | CXCR4 | |
| SCHEMBL3404509 | 0.76 | CXCR4 (0.69) | CXCR4 | |
| SCHEMBL3801910 | 0.76 | CXCR4 (0.46) | CXCR4 | |
| SCHEMBL5050990 | 0.76 | CXCR4 (0.48) | CXCR4 | |
| SCHEMBL5050995 | 0.76 | CXCR4 (0.48) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807694-B2 | Chemokine receptor binding heterocyclic compounds | GENZYME CORPORATION (US) | 2010-10-05 | — | — | US | disclosed |