Gluconic Acid

Gluconic Acid

SCHEMBL1312904

O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[BiH3].[KH]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.91
LMNA P02545 2/20 0.61
USP2 O75604 1/20 0.56
SLCO1B1 Q9Y6L6 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 2/20 0.48
CYP2C9 P11712 1/20 0.48
OR51E2 Q9H255 1/20 0.40
KDM4E B2RXH2 2/20 0.38
PGD P52209 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluconic Acid SCHEMBL6474250 0.98 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL1434160 0.98 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL15569419 0.98 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL8933262 0.98 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL27686780 0.98 PDE4A (0.95) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL9689598 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL9273926 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL16030008 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL2789971 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Gluconic Acid SCHEMBL14856448 0.95 PDE4A (0.91) PDE4ALMNAUSP2SLCO1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9170245-B2 Chemical indicator composition, indicators and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-10-27 US claimed
EP-2506006-A1 Chemical indicator composition, indicators and methods 3M Innovative Properties Company (US) 2012-10-03 EP claimed
US-20110275159-A1 CHEMICAL INDICATOR COMPOSITION, INDICATORS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-10 US claimed
EP-2382461-A2 CHEMICAL INDICATOR COMPOSITION, INDICATORS AND METHODS 3M Innovative Properties Company (US) 2011-11-02 EP claimed
WO-2010078422-A2 CHEMICAL INDICATOR COMPOSITION, INDICATORS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-07-08 WO claimed
US-11484614-B2 Water-based sterilization indicator composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-01 US disclosed
CN-108699374-B Water-based sterilization indicator composition 3M创新有限公司 2021-07-06 CN disclosed
EP-2795312-B1 WATER-BASED STERILIZATION INDICATOR COMPOSITION, METHOD FOR ITS PREPARATION AND INDICATOR TAPE 3M INNOVATIVE PROPERTIES CO (US) 2021-02-24 EP disclosed
US-20200324009-A1 WATER-BASED STERILIZATION INDICATOR COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-10-15 US disclosed
US-10736982-B2 Water-based sterilization indicator composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-08-11 US disclosed
US-20190008990-A1 WATER-BASED STERILIZATION INDICATOR COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-01-10 US disclosed
WO-2017127297-A1 WATER-BASED STERILIZATION INDICATOR COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-07-27 WO disclosed
EP-2583094-A1 INDICATOR FOR STERILIZATION PROCESS 3M Innovative Properties Company (US) 2013-04-24 EP disclosed
EP-2506006-A1 Chemical indicator composition, indicators and methods 3M Innovative Properties Company (US) 2012-10-03 EP disclosed
WO-2011163028-A1 INDICATOR FOR STERILIZATION PROCESS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-12-29 WO disclosed
US-20110312096-A1 CHEMICAL INDICATOR COMPOSITIONS, INDICATORS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2011-12-22 US disclosed
US-20110275159-A1 CHEMICAL INDICATOR COMPOSITION, INDICATORS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-10 US disclosed
EP-2382461-A2 CHEMICAL INDICATOR COMPOSITION, INDICATORS AND METHODS 3M Innovative Properties Company (US) 2011-11-02 EP disclosed
WO-2010078422-A2 CHEMICAL INDICATOR COMPOSITION, INDICATORS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-07-08 WO disclosed
US-4331518-A Bismuth composition, method of electroplating a tin-bismuth alloy and electroplating bath therefor VULCAN MATERIALS COMPANY (US) 1982-05-25 US disclosed