⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786196 | 0.72 | — | — | |
| Acetamide SCHEMBL30626021 | 0.70 | — | — | |
| Acetone SCHEMBL21835119 | 0.68 | — | — | |
| Acetone SCHEMBL29657100 | 0.68 | — | — | |
| SCHEMBL30490349 | 0.67 | — | — | |
| SCHEMBL31508509 | 0.67 | — | — | |
| SCHEMBL42149 | 0.67 | — | — | |
| SCHEMBL902574 | 0.67 | — | — | |
| SCHEMBL3273056 | 0.67 | — | — | |
| SCHEMBL15257797 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282547-A4 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | — | 1990-11-28 | — | — | EP | claimed |
| US-4820715-A | TREATING NAUSEA AND GASTRIC DISORDERS | BRISTOL-MYERS COMPANY (US) | 1989-04-11 | — | — | US | claimed |
| EP-0282547-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN. | ADRIA LAB INC (US) | 1988-09-21 | — | — | EP | claimed |
| US-4739049-A | Phosphorylation of cyclic amides | HOFFMANN-LA ROCHE INC. (US) | 1988-04-19 | — | — | US | claimed |
| WO-1988001866-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | ADRIA LABORATORIES, INC. (US) | 1988-03-24 | — | — | WO | claimed |
| CN-114585610-A | 2, 6-dioxo-3, 6-dihydropyrimidine compound, and agricultural and horticultural bactericide, nematicide, and medical and animal antifungal agent | 日本曹达株式会社 | 2022-06-03 | — | — | CN | disclosed |
| CN-108267576-B | Modified CCP antigen and use thereof, anti-CCP antibody detection kit and manufacturing method thereof | 深圳市新产业生物医学工程股份有限公司 | 2020-07-14 | — | — | CN | disclosed |
| US-8809538-B2 | Piperidine-containing compounds and use thereof | ARRAY BIOPHARMA INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8551956-B2 | Compositions containing peptides with non-natural amino acids and methods of use | AVON PRODUCTS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20110275608-A1 | PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2011-11-10 | — | — | US | disclosed |
| EP-2375899-A1 | PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF | Array Biopharma, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20100292483-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| US-5011992-A | Antiemetics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0282547-A4 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | — | 1990-11-28 | — | — | EP | disclosed |
| US-4820715-A | TREATING NAUSEA AND GASTRIC DISORDERS | BRISTOL-MYERS COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| US-4808624-A | ANTIEMETICS | BRISTOL-MYERS COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0282547-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN. | ADRIA LAB INC (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4772459-A | N-(PYRROLIDINYL-OR PIPERIDINYLALKYL) ETHER-SUBSTITUTED BENZAMIDES | ERBAMONT, INC. (US) | 1988-09-20 | — | — | US | disclosed |
| WO-1988001866-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | ADRIA LABORATORIES, INC. (US) | 1988-03-24 | — | — | WO | disclosed |
| US-3953436-A | 3,4-Dicarboxycephalosporins and derivatives | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | disclosed |