Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 6/20 | 0.52 |
| ▸ | PGR | P06401 | 5/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200096 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL29519614 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL3750546 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL17302786 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL13397495 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL12437208 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL8843324 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL12101456 | 1.00 | CYP17A1 (0.54) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL11747587 | 0.89 | AR (0.48) | CYP17A1ARPGRNR3C2MAPT | |
| SCHEMBL24711581 | 0.86 | MAPT (0.49) | CYP17A1ARPGRNR3C2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771462-B1 | A PROCESS FOR THE PREPARATION OF 7-ALPHA-ALKYLATED 19-NORSTEROIDS | SICOR INC (US) | 2010-09-29 | — | — | EP | disclosed |
| US-7790910-B2 | such as fulvestrant | SICOR INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-7790910-B2 | such as fulvestrant | SICOR INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090318721-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | MACDONALD PETER LINDSAY | 2009-12-24 | — | — | US | disclosed |
| US-20090318721-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | MACDONALD PETER LINDSAY | 2009-12-24 | — | — | US | disclosed |
| US-20090306417-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | SICOR INC. | 2009-12-10 | — | — | US | disclosed |
| US-20090306417-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | SICOR INC. | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306417-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | CYP19A1, CYP17A1, CYP4A11 | CYP17A1 2/4885AR 94/4885PGR 87/4885 |
| US-20090318721-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | CYP19A1, CYP17A1, CYP4A11 | CYP17A1 2/4885AR 94/4885PGR 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.