⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126945 | 0.78 | — | — | |
| SCHEMBL130530 | 0.78 | — | — | |
| SCHEMBL21499767 | 0.75 | — | — | |
| SCHEMBL3146943 | 0.73 | — | — | |
| SCHEMBL727837 | 0.71 | — | — | |
| SCHEMBL11103399 | 0.71 | — | — | |
| SCHEMBL17700630 | 0.71 | — | — | |
| SCHEMBL12668364 | 0.71 | — | — | |
| SCHEMBL16499903 | 0.71 | — | — | |
| SCHEMBL2958602 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| EP-1786552-A1 | METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY | Applera Corporation (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20060078983-A1 | Polymer monolith substrate | APPLERA CORPORATION (US) | 2006-04-13 | — | — | US | disclosed |
| WO-2006026378-A1 | METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY | APPLERA CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |