Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12141260 | 0.86 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL12141284 | 0.84 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL10592338 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL10592478 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL15325106 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL10591448 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL607461 | 0.82 | TP53 (0.42) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL1196679 | 0.82 | TP53 (0.42) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL1196880 | 0.82 | TP53 (0.42) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL10591095 | 0.81 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1TP53MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790700-B2 | Derivatives of partially desulphated glycosaminoglycans endowed with antiangiogenic activity and devoid of anticoagulating effect | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2010-09-07 | — | — | US | disclosed |