⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070791 | 1.00 | — | — | |
| SCHEMBL12163091 | 1.00 | — | — | |
| SCHEMBL10208832 | 0.92 | — | — | |
| SCHEMBL8320644 | 0.92 | — | — | |
| SCHEMBL2632448 | 0.92 | — | — | |
| SCHEMBL28681083 | 0.89 | — | — | |
| SCHEMBL1071315 | 0.78 | — | — | |
| SCHEMBL28903462 | 0.72 | — | — | |
| SCHEMBL13679880 | 0.72 | — | — | |
| SCHEMBL12128589 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483161-B1 | INTERMEDIATES USED TO MAKE ENTECAVIR | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-03-03 | — | — | EP | disclosed |
| EP-2594569-A1 | ENTECAVIR SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2013-05-22 | — | — | EP | disclosed |
| US-7807683-B2 | N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2010-10-05 | — | — | US | disclosed |
| US-20070054906-A1 | Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION | 2007-03-08 | — | — | US | disclosed |