SCHEMBL13147150

SCHEMBL13147150

CCOc1cccc(C(=O)NC(=N)NCCCCN2CCCC2)c1CCc1cc(Br)ccc1OC

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 16/20 0.58
▸ DRD2 P14416 3/20 0.42
▸ DRD4 P21917 3/20 0.42
▸ DRD3 P35462 3/20 0.42
▸ FPR3 P25089 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13180228 0.92 MC4R (0.48) MC4RDRD2DRD4DRD3FPR3
SCHEMBL13147075 0.89 MC4R (0.59) MC4RDRD2DRD4DRD3
SCHEMBL13147367 0.89 MC4R (0.73) MC4R
SCHEMBL14193791 0.88 MC4R (0.72) MC4R
SCHEMBL13147074 0.87 MC4R (0.58) MC4RDRD2DRD4DRD3
SCHEMBL3090271 0.86 MC4R (0.72) MC4R
SCHEMBL3089431 0.84 MC4R (0.71) MC4RDRD3
SCHEMBL3082130 0.82 MC4R (0.72) MC4RDRD3
SCHEMBL13147365 0.81 MC4R (0.62) MC4R
SCHEMBL13147348 0.81 MC4R (0.64) MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790719-B2 Modulators of melanocortin receptor ORE PHARMACEUTICALS, INC. (US) 2010-09-07 — — US disclosed
US-7365070-B2 Modulators of melanocortin receptor ORE PHARMACEUTICALS INC. (US) 2008-04-29 — — US disclosed
US-7365070-B2 Modulators of melanocortin receptor ORE PHARMACEUTICALS INC. (US) 2008-04-29 — — US disclosed
US-20070293498-A1 Modulators of melanocortin receptor GENE LOGIC, INC. (US) 2007-12-20 — — US disclosed
US-20070293498-A1 Modulators of melanocortin receptor GENE LOGIC, INC. (US) 2007-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293498-A1 Modulators of melanocortin receptor MC4R, MC1R, MC5R MC4R 1/4885DRD2 244/4885DRD4 405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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