SCHEMBL13147268

SCHEMBL13147268

COc1ccc(Br)cc1CCc1c(F)cccc1C(=O)NC(=N)NCC1CCN(CC2CCCC2)CC1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 18/20 0.62
▸ ACHE P22303 2/20 0.48
▸ HTR4 Q13639 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13147218 0.97 MC4R (0.63) MC4RACHEHTR4
SCHEMBL13147230 0.91 MC4R (0.58) MC4R
SCHEMBL13147326 0.91 MC4R (0.65) MC4R
SCHEMBL13147325 0.90 MC4R (0.62) MC4R
SCHEMBL14223835 0.90 MC4R (0.60) MC4R
SCHEMBL13147246 0.89 MC4R (0.61) MC4R
SCHEMBL13147186 0.88 MC4R (0.52) MC4RACHEHTR4
SCHEMBL13147319 0.87 MC4R (0.58) MC4R
SCHEMBL13147210 0.87 MC4R (0.71) MC4R
SCHEMBL13147235 0.85 MC4R (0.56) MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790719-B2 Modulators of melanocortin receptor ORE PHARMACEUTICALS, INC. (US) 2010-09-07 — — US disclosed
US-7790719-B2 Modulators of melanocortin receptor ORE PHARMACEUTICALS, INC. (US) 2010-09-07 — — US disclosed
US-7365070-B2 Modulators of melanocortin receptor ORE PHARMACEUTICALS INC. (US) 2008-04-29 — — US disclosed
US-7365070-B2 Modulators of melanocortin receptor ORE PHARMACEUTICALS INC. (US) 2008-04-29 — — US disclosed
US-20070293498-A1 Modulators of melanocortin receptor GENE LOGIC, INC. (US) 2007-12-20 — — US disclosed
US-20070293498-A1 Modulators of melanocortin receptor GENE LOGIC, INC. (US) 2007-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293498-A1 Modulators of melanocortin receptor MC4R, MC1R, MC5R MC4R 1/4885ACHE 4147/4885HTR4 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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