SCHEMBL131484

SCHEMBL131484

CCCCCC#CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2973161 0.97 PTPN7 (0.46)
SCHEMBL2969999 0.97 PTPN7 (0.46)
SCHEMBL2974627 0.97 PTPN7 (0.46)
SCHEMBL128401 0.97
SCHEMBL129929 0.97 PTPN7 (0.46)
SCHEMBL132677 0.97 PTPN7 (0.46)
SCHEMBL128487 0.97 PTPN7 (0.46)
SCHEMBL2961498 0.97 PTPN7 (0.46)
SCHEMBL2966558 0.97 PTPN7 (0.46)
SCHEMBL130464 0.97 PTPN7 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2736514-B1 ALKYNYL SUBSTITUTED PYRIMIDINYL-PYRROLES ACTIVE AS KINASES INHIBITORS NERVIANO MEDICAL SCIENCES SRL (IT) 2017-10-18 EP claimed
US-8912200-B2 Alkynyl substituted pyrimidinyl-pyrroles active as kinases inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2014-12-16 US claimed
US-20140194406-A1 ALKYNYL SUBSTITUTED PYRIMIDINYL-PYRROLES ACTIVE AS KINASES INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2014-07-10 US claimed
EP-2736514-A1 ALKYNYL SUBSTITUTED PYRIMIDINYL-PYRROLES ACTIVE AS KINASES INHIBITORS Nerviano Medical Sciences S.r.l. (IT) 2014-06-04 EP claimed
WO-2013014039-A1 ALKYNYL SUBSTITUTED PYRIMIDINYL-PYRROLES ACTIVE AS KINASES INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2013-01-31 WO claimed
US-6225499-B1 REACTING N-ARYLMETHYLIDENE AMINOARYLBROMIDE WITH TERMINAL ACETYLENE IN PRESENCE OF BASE AND CATALYST SYSTEM COMPRISING PALLADIUM CATALYST AND CUPROUS SALT TO PRODUCE N-ARYLMETHYLIDENE AMINOARYLACETYLENE CATALYTICA PHARMACEUTICALS, INC. 2001-05-01 US claimed
CN-1267282-A Process for preparing aminoarylacetylenes CATALYTICA PHARMACEUTICALS INC (US) 2000-09-20 CN claimed
EP-1019359-A2 PROCESS FOR PREPARING AMINOARYLACETYLENES Catalytica Pharmaceuticals, Inc. (US) 2000-07-19 EP claimed
WO-1999003803-A2 PROCESS FOR PREPARING AMINOARYLACETYLENES CATALYTICA PHARMACEUTICALS, INC. (US) 1999-01-28 WO claimed
EP-0008194-B1 ETHYNYL-TERMINATED EPOXY RESIN DERIVATIVES AND PROCESS FOR MAKING THE SAME Hughes Aircraft Company (US) 1983-03-30 EP claimed
US-4218555-A FORMATION OF AMINE SALT, HEATING TO FORM CYCLIC IMIDE GULF OIL CORPORATION (US) 1980-08-19 US claimed
EP-0008194-A1 Ethynyl-terminated epoxy resin derivatives and process for making the same Hughes Aircraft Company (US) 1980-02-20 EP claimed
US-4183869-A Ethynyl-terminated epoxy resin derivatives and process for making the same HUGHES AIRCRAFT COMPANY (US) 1980-01-15 US claimed
US-4180649-A LOW TEMPERATURE, POLYACETYLENES, ACETYLENIC POLYMERS, POLYIMINES HUGHES AIRCRAFT COMPANY (US) 1979-12-25 US claimed
US-4108836-A Process for synthesizing acetylene-substituted polyimides and polyimides thereof HUGHES AIRCRAFT COMPANY (US) 1978-08-22 US claimed
US-4097456-A Preparation of acetylene-substituted polyimide oligomers and polyimide polymers GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-06-27 US claimed
CN-119346177-A High-selectivity catalyst, preparation method and application in ethylene oligomerization 广东新华粤石化集团股份公司 2025-01-24 CN disclosed
CN-114213272-B Synthetic method of arylethynyl formamide compound 江南大学 2022-12-27 CN disclosed
US-4097456-A Preparation of acetylene-substituted polyimide oligomers and polyimide polymers GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-06-27 US disclosed
US-4097456-A Preparation of acetylene-substituted polyimide oligomers and polyimide polymers GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-06-27 US disclosed