Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13150051 | 1.00 | KDM4E (0.40) | KDM4ESMN1; SMN2TSHRTDP1 | |
| SCHEMBL13149131 | 0.98 | KDM4E (0.41) | KDM4ESMN1; SMN2TSHRTDP1 | |
| SCHEMBL13150047 | 0.90 | KDM4E (0.38) | KDM4ESMN1; SMN2TSHRTDP1 | |
| SCHEMBL13150046 | 0.89 | KDM4E (0.40) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL13149117 | 0.88 | TSHR (0.36) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL13150052 | 0.81 | TSHR (0.36) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL13149119 | 0.81 | KDM4E (0.39) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL13149132 | 0.79 | TSHR (0.37) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL1470689 | 0.78 | — | — | |
| SCHEMBL13149129 | 0.76 | TDP1 (0.33) | KDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234552-A1 | POLYOL COMPOUND, TRANSPARENT MOLDED ARTICLE AND METHOD OF MANUFACTURING TRANSPARENT MOLDED ARTICLE | HOYA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |