Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15977503 | 0.95 | PIK3CA (0.41) | PIK3CAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10301100 | 0.94 | PIK3CA (0.42) | PIK3CAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10301055 | 0.92 | MAPK13 (0.41) | PIK3CAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10301085 | 0.91 | MAPK11 (0.42) | PIK3CAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29774095 | 0.84 | NOTUM (0.56) | PIK3CAMAPK14MKNK1IMPDH2NOTUM | |
| SCHEMBL15977469 | 0.84 | NOTUM (0.56) | PIK3CAMAPK14MKNK1IMPDH2NOTUM | |
| SCHEMBL10030021 | 0.84 | NOTUM (0.56) | PIK3CAMAPK14MKNK1IMPDH2NOTUM | |
| SCHEMBL10300979 | 0.84 | NOTUM (0.56) | PIK3CAMAPK14MKNK1IMPDH2NOTUM | |
| SCHEMBL10030050 | 0.84 | NOTUM (0.56) | PIK3CAMAPK14MKNK1IMPDH2NOTUM | |
| SCHEMBL13158596 | 0.84 | NOTUM (0.56) | PIK3CAMAPK14MKNK1IMPDH2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114263-A2 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DOW ADVANCED DISPLAY MATERIALS,LTD. (KR) | 2010-10-07 | — | — | WO | disclosed |