Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 17/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160205 | 1.00 | BDKRB1 (0.38) | BDKRB1CNR1BRAFBACE1 | |
| SCHEMBL2809516 | 0.93 | BDKRB1 (0.42) | BDKRB1CNR1 | |
| SCHEMBL2809518 | 0.93 | BDKRB1 (0.42) | BDKRB1CNR1 | |
| SCHEMBL2810338 | 0.91 | BDKRB1 (0.38) | BDKRB1CNR1 | |
| SCHEMBL2810341 | 0.91 | BDKRB1 (0.38) | BDKRB1CNR1 | |
| SCHEMBL13129055 | 0.91 | BDKRB1 (0.38) | BDKRB1CNR1 | |
| SCHEMBL2808638 | 0.91 | BDKRB1 (0.43) | BDKRB1CNR1 | |
| SCHEMBL2808635 | 0.91 | BDKRB1 (0.43) | BDKRB1CNR1 | |
| SCHEMBL2810098 | 0.91 | BDKRB1 (0.38) | BDKRB1CNR1 | |
| SCHEMBL13129059 | 0.91 | BDKRB1 (0.38) | BDKRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |