Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13161573 | 0.93 | PTGDR2 (0.44) | PTGDR2MAPTPTPN1TP53LMNA | |
| SCHEMBL13160846 | 0.92 | PTGDR2 (0.46) | PTGDR2PTPN1CA12CA1CA2 | |
| SCHEMBL13160863 | 0.92 | PTGDR2 (0.46) | PTGDR2MAPTPTPN1FFAR1CA12 | |
| SCHEMBL13160872 | 0.91 | PTGDR2 (0.44) | PTGDR2MAPTPTPN1FFAR1 | |
| SCHEMBL13160702 | 0.91 | PTGDR2 (0.44) | PTGDR2PTPN1FFAR1 | |
| SCHEMBL2773676 | 0.91 | PTGDR2 (0.53) | PTGDR2MAPTPTPN1TP53LMNA | |
| SCHEMBL13160878 | 0.91 | PTGDR2 (0.47) | PTGDR2CA12CA1CA2CA4 | |
| SCHEMBL13160869 | 0.90 | PTGDR2 (0.44) | PTGDR2MAPTPTPN1TP53LMNA | |
| SCHEMBL13160800 | 0.90 | PTGDR2 (0.45) | PTGDR2MAPTPTPN1FFAR1 | |
| SCHEMBL13160865 | 0.89 | PTGDR2 (0.44) | PTGDR2PTPN1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102154-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-09-10 | — | — | WO | disclosed |