Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165998 | 0.93 | BDKRB1 (0.44) | BDKRB1EPHX2HPGDSPOLBP2RX7 | |
| SCHEMBL13165601 | 0.93 | BDKRB1 (0.44) | BDKRB1EPHX2HPGDSPOLBP2RX7 | |
| SCHEMBL2812285 | 0.91 | POLB (0.36) | BDKRB1EPHX2HPGDSPOLBP2RX7 | |
| SCHEMBL2788500 | 0.91 | BDKRB1 (0.43) | BDKRB1EPHX2HPGDSPOLBP2RX7 | |
| SCHEMBL764412 | 0.91 | BDKRB1 (0.53) | BDKRB1EPHX2HPGDSPOLBP2RX7 | |
| SCHEMBL13165609 | 0.90 | BDKRB1 (0.42) | BDKRB1EPHX2HPGDSPOLBP2RX7 | |
| SCHEMBL2790340 | 0.90 | BDKRB1 (0.46) | BDKRB1EPHX2HPGDSPOLBPPARG | |
| SCHEMBL13165603 | 0.89 | BDKRB1 (0.45) | BDKRB1EPHX2HPGDSPOLBPPARG | |
| Trifluoroacetic Acid SCHEMBL2787349 | 0.89 | POLB (0.35) | BDKRB1EPHX2POLBP2RX7PPARG | |
| SCHEMBL13165755 | 0.88 | BDKRB1 (0.44) | BDKRB1EPHX2HPGDSPOLBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |