Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 8/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186139 | 0.94 | OPRL1 (0.36) | BDKRB1NTRK1OPRL1HDAC1 | |
| SCHEMBL2812435 | 0.94 | OPRL1 (0.36) | BDKRB1NTRK1OPRL1HDAC1 | |
| SCHEMBL186328 | 0.93 | CNR2 (0.35) | BDKRB1NTRK1PDE2AOPRL1 | |
| SCHEMBL2805102 | 0.93 | CNR2 (0.35) | BDKRB1NTRK1PDE2AOPRL1 | |
| SCHEMBL13166245 | 0.88 | OPRL1 (0.35) | BDKRB1NTRK1OPRL1HDAC1 | |
| SCHEMBL185775 | 0.88 | OPRL1 (0.35) | BDKRB1NTRK1OPRL1 | |
| SCHEMBL2808195 | 0.88 | OPRL1 (0.35) | BDKRB1NTRK1OPRL1 | |
| SCHEMBL2811472 | 0.85 | BDKRB1 (0.35) | BDKRB1OPRL1HDAC1 | |
| SCHEMBL2811476 | 0.85 | BDKRB1 (0.35) | BDKRB1OPRL1HDAC1 | |
| SCHEMBL13128561 | 0.85 | OPRL1 (0.36) | BDKRB1OPRL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | BDKRB1 289/4885NTRK1 4210/4885PDE2A 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.