Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.63 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.63 |
| ▸ | ITGAL | P20701 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10130071 | 0.94 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL12719224 | 0.93 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL10129876 | 0.92 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL879401 | 0.86 | ITGB2 (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL12048775 | 0.85 | ITGB2 (0.61) | ITGB2ICAM1ITGAL | |
| SCHEMBL10130081 | 0.84 | ITGB2 (0.61) | ITGB2ICAM1ITGAL | |
| SCHEMBL16307470 | 0.83 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL10130084 | 0.83 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL10130097 | 0.83 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL10130096 | 0.83 | ITGB2 (0.59) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790743-B2 | Modulators of cellular adhesion | SARCODE CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-7314938-B2 | Immune and/or inflammatory disorders; autoimmune disorders; disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1); antagonize CD11/CD18 receptors associated with leukocytes. | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-01-01 | — | — | US | disclosed |