Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | HTR1A | P08908 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168904 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168900 | 0.95 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL28386689 | 0.94 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL14366679 | 0.94 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168898 | 0.94 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13186178 | 0.91 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13186116 | 0.91 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL11226250 | 0.90 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL8637822 | 0.90 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL8637826 | 0.90 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799830-B2 | Cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-09-21 | — | — | US | disclosed |