Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.84 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.62 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | FAP | Q12884 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160799 | 1.00 | DPP4 (0.84) | DPP4DPP9DPP8DPP7ACE | |
| Hydrochloric Acid SCHEMBL2854161 | 0.99 | DPP4 (0.83) | DPP4DPP9DPP8DPP7ACE | |
| Hydrochloric Acid SCHEMBL2854157 | 0.99 | DPP4 (0.83) | DPP4DPP9DPP8DPP7ACE | |
| Retagliptin SCHEMBL30438226 | 0.92 | DPP4 (1.00) | DPP4DPP9DPP8DPP7ACE | |
| Retagliptin SCHEMBL193599 | 0.92 | DPP4 (1.00) | DPP4DPP9DPP8DPP7ACE | |
| Retagliptin SCHEMBL193600 | 0.92 | DPP4 (1.00) | DPP4DPP9DPP8DPP7ACE | |
| SCHEMBL10160854 | 0.91 | DPP4 (0.75) | DPP4DPP9DPP8DPP7ACE | |
| SCHEMBL13175151 | 0.91 | DPP4 (0.75) | DPP4DPP9DPP8DPP7ACE | |
| Retagliptin SCHEMBL2862768 | 0.91 | DPP4 (0.98) | DPP4DPP9DPP8DPP7ACE | |
| Retagliptin SCHEMBL2862766 | 0.91 | DPP4 (0.98) | DPP4DPP9DPP8DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230241-A1 | TETRAHYDRO-IMIDAZOÝ1,5-A¨PYRAZINE DERIVATIVES, PREPARATION METHODS AND MEDICAL USES THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2010-09-22 | — | — | EP | disclosed |