Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.77 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.63 |
| ▸ | ACE | P12821 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | FAP | Q12884 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160735 | 1.00 | DPP4 (0.77) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL2855596 | 0.99 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL2855594 | 0.99 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL16258116 | 0.93 | DPP4 (0.77) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL10160777 | 0.93 | DPP4 (0.77) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL10160762 | 0.93 | DPP4 (0.77) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL2858216 | 0.92 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL2858218 | 0.92 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL2860850 | 0.92 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE | |
| Hydrochloric Acid SCHEMBL2860853 | 0.92 | DPP4 (0.76) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230241-A1 | TETRAHYDRO-IMIDAZOÝ1,5-A¨PYRAZINE DERIVATIVES, PREPARATION METHODS AND MEDICAL USES THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2010-09-22 | — | — | EP | disclosed |