Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175651 | 0.86 | AKR1C3 (0.69) | AKR1C3MEN1KMT2ANPC1 | |
| SCHEMBL13100272 | 0.84 | AKR1C3 (0.75) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13175659 | 0.81 | AKR1C3 (0.70) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3101848 | 0.77 | AKR1C3 (1.00) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13100324 | 0.76 | AKR1C3 (0.77) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13174450 | 0.75 | AKR1C3 (0.79) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3112510 | 0.75 | AKR1C3 (0.80) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13174355 | 0.75 | AKR1C3 (0.75) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13173656 | 0.73 | AKR1C3 (0.79) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13175495 | 0.73 | AKR1C3 (0.54) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |