Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175716 | 0.92 | AKR1C3 (0.67) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL13175469 | 0.88 | AKR1C3 (0.66) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL13175505 | 0.87 | AKR1C3 (0.69) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL13175503 | 0.83 | AKR1C3 (0.56) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL13175672 | 0.83 | AKR1C3 (0.73) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3104370 | 0.83 | AKR1C3 (1.00) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL3106410 | 0.82 | AKR1C3 (0.72) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL13175507 | 0.82 | AKR1C3 (0.66) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL13174701 | 0.81 | AKR1C3 (0.71) | AKR1C3MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL13174677 | 0.81 | AKR1C3 (0.71) | AKR1C3MEN1KMT2AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101128-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |